Meso America would be good - again it's not an often done culture. It's inherent interdependency would make for an interesting variable.
But what does "Historic America" mean? I am at a bit of a loss to even make a guess!
If you mean the area that is today the USA, you've got predominantly nomadic peoples which wouldnt make for a fun city building game... or peoples like the Cahokia who settled and possibly made a city as large as 20000, but we have very little idea about any buildings. Aside from the Pueblo indians (again a poor CB context) I really can't see how what is today's USA could be the focus for any sort of ancient city building game.
But for a rarely done truly "great" civilisation, I think it is really time that India got the CB treatment. An ancient high watermark of civilisation that is so often ignored in the West - they had massive city states, wars, built major constructions, had castes, a systematic religion and codex, commerce and governmental structures while we in the west were mostly only getting together to hunt down mammoths, to sacrifice some goats and to show off our new seal skin loincloth.
Going from the proto ancient Harrapan's or Indus Valley civilisation, you could trace the development through to the Iron Age - the Vedic period.
EDIT: Added linky http://en.wikipedia.org/wiki/Indus_Valley_Civilization
and a quote from it (my bold)
A sophisticated and technologically advanced urban culture is evident in the Indus Valley Civilization. The quality of municipal town planning
suggests knowledge of urban planning and efficient municipal governments
which placed a high priority on hygiene
. The streets of major cities such as Mohenjo-daro or Harappa were laid out in perfect grid patterns
. The houses were protected from noise, odors, and thieves.
As seen in Harappa, Mohenjo-daro and the recently discovered Rakhigarhi, this urban plan included the world's first urban sanitation systems
. Within the city, individual homes or groups of homes obtained water from wells
. From a room that appears to have been set aside for bathing, waste water was directed to covered drains, which lined the major streets. Houses opened only to inner courtyards and smaller lanes.
The ancient Indus systems of sewerage and drainage that were developed and used in cities throughout the Indus Empire, were far more advanced than any found in contemporary urban sites in the Middle East and even more efficient than those in some areas of Pakistan and India today. The advanced architecture of the Harappans is shown by their impressive dockyards, granaries, warehouses, brick platforms and protective walls
. The massive citadels of Indus cities that protected the Harappans from floods and attackers were larger than most Mesopotamian ziggurats.
The purpose of the citadel remains debated. In sharp contrast to this civilization's contemporaries, Mesopotamia and Ancient Egypt, no large monumental structures were built. There is no conclusive evidence of palaces or temples - or of kings, armies, or priests. Some structures are thought to have been granaries. Found at one city is an enormous well-built bath, which may have been a public bath
. Although the citadels were walled, it is far from clear that these structures were defensive. They may have been built to divert flood waters.
Most city dwellers appear to have been traders or artisans
, who lived with others pursuing the same occupation in well-defined neighborhoods
. Materials from distant regions
were used in the cities for constructing seals, beads and other objects. Among the artifacts discovered were beautiful beads of glazed stone called faïence. The seals have images of animals, gods and other types of inscriptions. Some of the seals were used to stamp clay on trade goods and most probably had other uses.
This would rapidly lead into the Vedic civilisations with more stuctured religion, rulers and states.
This just screams City Builder to me!!